The Chronic Renal Insufficiency Cohort Study targets risk factors for progression of chronic kidney disease and cardiovascular disease to provide researchers with new ways of understanding CKD.

The CRIC study provides unique and valuable knowledge about chronic kidney disease

The CRIC Study was established in 2001 by the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) to improve the understanding of chronic kidney disease (CKD) and related cardiovascular illness. The study’s goals are:
  • To examine risk factors for progression of CKD and cardiovascular disease,
  • To develop models that identify high-risk subgroups,
  • To assist in the development of treatment trials and therapies.
The CRIC Study initially enrolled over 3939 people with CKD who remain in long-term follow-up. Between July 2013 and August 2015, an additional 1560 people with CKD were invited to join the study with an emphasis on older Americans. The focus of the study was modified to emphasize early forms of CKD and the impact of CKD on multiple dimensions of health status. Follow-up of study participants continues at eleven CRIC Study Centers.

CRIC Collaborations

The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples.
Learn more about collaborating with CRIC >>


Associations of conventional echocardiographic measures with incident heart failure and mortality: the Chronic Renal Insufficiency Cohort

Clin J Am Soc Nephrol.
2017 Jan 6;12(1):60-68.
doi: 10.2215/CJN.02700316.
Epub 2016 Nov 10.

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