health professionals participate in research of chronic kidney disease

Chronic Renal Insufficiency Cohort (CRIC) Study Opportunity Pool Program

We are accepting applications to fund highly innovative studies using CRIC participant data, led by investigators in any scientific or clinical discipline. Applications for studies addressing topic areas not fully explored in prior CRIC investigations and that promise significant potential health impact are encouraged. Applications may address a broad array of topics, but those focused on the following areas/approaches are particularly encouraged:

  • Innovative studies utilizing existing multi-omics data such as genomics, metabolomics and proteomics, to help identify disease subgroups or pathways associated with CKD progression and/or CVD outcomes are highly encouraged.
  • Innovative measures and analytic approaches to allow for sub-phenotyping of CKD subgroups. Can be based on either existing or newly collected data including the laboratory analysis of existing biospecimens..
  • Broadening the range of scientific approaches through novel reanalysis of complex imaging data such as echocardiogram measures, CT, MRI.

Applications focused on biomarker research will not be accepted.

The Chronic Renal Insufficiency Cohort (CRIC) Study Opportunity Pool Program IS NOW ACCEPTING APPLICATIONS. Letters of intent are due on
March 29, 2021.

To aid you as you prepare your submission, please refer to the following resources:


Please use this link to upload your letter of intent.



For questions, please contact:

Chronic Renal Insufficiency Cohort Study
Scientific and Data Coordinating Center
Perelman School of Medicine at
The University of Pennsylvania
cricprog@pennmedicine.upenn.edu

CRIC Scientific Discoveries

FGF23 elevation has been linked to greater risks of left ventricular hypertrophy (LVH) and mortality in patients with chronic kidney disease (CKD), but whether these risks represent causal effects of FGF23 is unknown. Here, we report that elevated FGF23 levels are independently associated with prevalent and incident LVH among CRIC Study participants.
Learn more >>

CRIC Collaborations

The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples.
Learn more about collaborating with CRIC >>
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